个人简介
2005年于内蒙古大学获理学学士学位；同年保送中国科学院成都有机化学研究所硕博连读，师从龚流柱教授从事不对称催化反应研究，于2010年7月获有机化学博士学位；2010年7月-2013年1月在美国纽约州立大学布法罗分校Qing Lin教授课题组从事化学生物学的博士后研究。曾获得2010年度“中国科学院朱李月华优秀博士生奖学金”、2011年度“中国科学院百篇优秀博士论文奖”。先后在J. Am. Chem. Soc; Angew. Chem. Int. Ed; ACS Chemical Biology; Org. Biomol. Chem; Chem. Commun.等国际一流学术期刊上发表多篇论文。
目前主要开展有机合成化学及化学生物学研究，包括新型生物正交反应的开发及功能有机探针的设计、合成及生物学应用研究。
在研项目
1. 国家自然科学基金面上项目，65万，在研，主持.
2. 中央高校重点项目，18万，在研，主持.
3. 陕西师范大学科研启动基金，60万，在研，主持.
4. 国家自然科学基金青年项目，25万，已结题，主持.
5. 陕西省自然科学基金青年项目，3万，已结题，主持.
6. 中央高校一般项目，9万，已结题，主持.
代表性成果
1. Na Zhao*, Pengfei Li, Jiabao Zhuang, Yanyan Liu, Yuxin Xiao, Ruilin Qin, Nan Li*, Aggregation-Induced Emission Luminogens with the Capability of Wide Color Tuning, Mitochondrial and Bacterial Imaging, Photodynamic Anticancer and Antibacterial Therapy. ACS applied materials & interfaces., 2019, DOI: 10.1021/acsami.9b01655.
2. Nan Li, Yanyan Liu, Yan Li, Jiabao Zhuang, Rongrong Cui, Qian Gong, Na Zhao*, Ben Zhong Tang*, Fine Tuning of Emission Behavior, Self-Assembly, Anion Sensing, and Mitochondria Targeting of Pyridinium-Functionalized Tetraphenylethene by Alkyl Chain Engineering. ACS Appl. Mater. Interfaces., 2018, 10, 24249–24257.
3. Rongrong Cui, Yuanchao Lv, Yong Sheng Zhao, Na Zhao*, Nan Li*, Solid-state fluorescent materials based on coumarin derivatives: polymorphism, stimuli-responsive emission, self-assembly and optical waveguides. Mater. Chem. Front., 2018,2, 910-916. (Materials Chemistry Frontiers HOT articles for 2018).
4. Ruixue Zhang, Pengfei Li, Wenjuan Zhang, Nan Li*, Na Zhao*, A highly sensitive fluorescent sensor with aggregation-induced emission characteristics for the detection of iodide and mercury ions in aqueous solution. J. Mater. Chem. C., 2016, 4, 10479-10485.
5. Nan Li*, Honglian Feng, Qian Gong, Chunxiao Wu, Hao Zhou, Zhiyan Huang, Jun Yang, Xiaohua Chen, Na Zhao, BINOL-based chiral aggregation-induced emission luminogens and their application in detecting copper(II) ions in aqueous media. J. Mater. Chem. C., 2015, 3, 11458-11463.
6. Na Zhao, Qian Gong, Ruixue Zhang, Jun Yang, Zhiyan Huang, Nan Li*, Ben Zhong Tang, A fluorescent probe with aggregation-induced emission characteristics for distinguishing homocysteine over cysteine and glutathione. J. Mater. Chem. C., 2015, 3, 8397-8402.
7. Nan Li, Carlo P. Ramil, Reyna K. V. Lim, and Qing Lin*, A Genetically Encoded Alkyne Directs Palladium-Mediated Protein Labeling on Live Mammalian Cell Surface. ACS Chem. Biol., 2015, 10, 379-384.
8. Nan Li, Reyna K. V. Lim, Selvakumar Edwardraja, Qing Lin*, Copper-Free Sonogashira Cross-Coupling for Functionalization of Alkyne-Encoded Proteins in Aqueous Medium and in Bacterial Cells. J. Am. Chem. Soc., 2011. 133. 15316-15319 (Highlighted in ChemBioChem. 2012, 13, 1728-1731).
9. Nan Li, Xiao-Hua Chen, Shi-Ming Zhou, Shi-Wei Luo, Jin Song, Lei Ren and Liu-Zhu Gong* Asymmetric Amplification in Phosphoric Acid Catalyzed Reactions. Angew Chem Int Ed., 2010, 49, 6378-6381. (Highlighted in Synfacts. 2010, 10, 1189-1189).
10. Nan Li, Jin Song, Xi-Feng Tu, Bin Liu, Xiao-Hua Chen and Liu-Zhu Gong*, Organocatalytic Asymmetric Intramolecular [3+2] Cycloaddition: A Straightforward Approach to Access Multiply Substituted Hexahydrochromeno[4,3-b]pyrrolidine Derivatives in High Optical Purity. Org. Biomol. Chem., 2010, 8, 2016-2019.
11. Nan Li, Xiao-Hua Chen, Jin Song, Shi-Wei Luo*, Wu Fan and Liu-Zhu Gong*, Highly Enantioselective Organocatalytic Biginelli and Biginelli-Like Condensations: Reversal of the Stereochemistry by Tuning the 3,3′-Disubstituents of Phosphoric Acids. J. Am. Chem. Soc., 2009. 131. 15301-1531
12. Jingnan Zhang, Hui Kang, Nan Li, Shiming Zhou, Huaming Sun, Shiwei Yin, Na Zhao, Ben Zhong Tang, Organic solid fluorophores regulated by subtle structure modification: color-tunable and aggregation-induced emission. Chem. Sci., 2017, 8, 577-582.
13. Reyna K.V. Lim, Nan Li, Carlo P. Ramil and Qing Lin*, Fast and sequence-specific palladium-mediated cross-couping reaction identified from phage display. ACS Chem. Biol., 2014, 9, 2139-2148.
14. Gang Cheng, Reyna K. V. Lim, Nan Li, Qing Lin*, Storable Palladacycles for Selective Functionalization of Alkyne-Containing Proteins. Chem. Commun., 2013. 49. 6809-6811.
15. Avinash Muppidi, Hongtao Zhang, Francesca Curreli, Nan Li, Asim K. Debnath and Qing Lin*, Design of antiviral stapled peptides containing a biphenyl cross-linker. Bioorg. Med. Chem. Lett., 2014, 24, 1748-1751.
